Synthesis of chromones and related compounds.
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Synthesis of chromones and related compounds.

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Published by University of Salford in Salford .
Written in English


Book details:

Edition Notes

PhD thesis, Chemistry.

SeriesD1519/71
ID Numbers
Open LibraryOL20308732M

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Chromones, six-membered oxygen heterocycles, and pyrazoles, five-membered two-adjacentnitrogen- containing heterocycles, represent two important classes of biologically active compounds. Certain derivatives of these scaffolds play an important role in medicinal chemistry and have been extensively used as versatile building blocks in organic synthesis. In this Cited by: 6. The condensation of phenols with β-keto esters to form chromones is known as the Simonois reaction and is closely related to the Pechmann synthesis of coumarins, and as a consequence, mixtures of both coumarins and chromones are usually ave irradiation is effective for promoting the reaction of phloroglucinol with β-keto . In recent years, scientific interest towards chromones (2), isoflavones (9) and homoisoflavones (10) has in-creased. It is due to the limited distribution of these compounds in the plant kingdom and possible the health ef-fect these compounds exhibit. The development of new methodologies for the synthesis of these compounds is Size: 3MB. Chromones (4H-chromenones) are a group of naturally occurring compounds ubiquitous in plants, and the chromone core has proven to be a privileged scaffold in medicinal : G. P. Ellis.

An efficient synthesis of 3-aminochromones and 3-alkylchromones by a N-heterocyclic carbene (NHC) catalyzed intramolecular hydroacylation reaction of corresponding salicylaldehyde derived nitriles and activated alkynes respectively in ionic liquids under microwave conditions is reported. This protocol has thAuthor: Nithya Murugesh, Jebiti Haribabu, Krishnamoorthy Arumugam, Chandrasekar Balachandran, Rajagopal Swaa. General Methods of Preparing Chromones. G. P. Ellis. Department of Chemistry, University of Wales Institute of Science and Technology, Cardiff Book Series: Chemistry of Heterocyclic Compounds: A Series Of Monographs. About. PDF. Tools. Synthesis of 4‐Thiochromones. Chemistry of Heterocyclic Compounds: Chromenes, Chromanones, and Cited by: 4. A general and efficient visible-light-induced CF2 radical-based cascade reaction of o-hydroxyaryl enaminones has been described. This protocol afforded the corresponding functionalized 3-CF2-containing chromones in generally good yields under mild reaction conditions. The use of NaHSO3, which has both basicity and reducibility, efficiently suppressed the formation of two Cited by: 8. Thorough explanations of synthesis from kinetic and thermodynamic viewpoints are included. The syntheses used are well tested and cover a broad range of interesting compounds that can be studied with a wide variety of physical techniques. The book covers 39 syntheses involving the preparation of 50 interesting by:

Wiley Online Library is migrating to a new platform powered by Atypon, the leading provider of scholarly publishing platforms. The new Wiley Online Library will be migrated over the weekend of February 24 and 25 and will be live on Febru Synthetic chromone precursors, i.e. chalcones, and related dienones were evaluated as antiproliferative agents that interfere with the tubulin-microtubule equilibrium, crucial for cellular mitosis. It was shown that several of the synthesized compounds destabilize tubulin assembly. Chemical synthesis, the construction of complex chemical compounds from simpler ones. It is the process by which many substances important to daily life are obtained. It is applied to all types of chemical compounds, but most syntheses are of organic molecules. Read More on This Topic. chemical compound: Chemical synthesis. Chromones play an important role in the design and discovery of new pharmacologically active compounds. A large volume of reports dedicated to synthesis and .